Central Dogma of Molecular Biology
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Tying it all together.....Watch & Listen as Paul Andersen connects the two vital cellular processes.

Culminating Project

Now that you have spend significant time studying the Central Dogma of Molecular Biology, let's have a little fun! With your small group, you will use modeling clay (or Play-Doh) and one of our Flip cameras or a digital camera of your own to create a Claymation (sometimes called stopmotion) movie about either transcription and translation.
What is a Stopmotion movie you ask? Click here to learn about them. For additional help with video editing or learning about the Central Dogma concepts, check out the 'Additional Resources' page.

Claymation Movie

In this activity, your group will use Play-Doh to model the either transcription or translation in eukaryotes.  For each model, you will use a digital camera to capture images as you model the process. These images along with labels, a narration, and any additional special effects will then be turned into a claymation movie by your group. All group members’ voices must be heard in the narration of the modeled process. It is expected that all members also contribute to the video editing that must be completed. Below you will find a list of structures/processes that need to be included (for each respective process) in your movie, as well a rubric for this activity.

Transcription

Pre-mRNA & mRNA
RNA plymerase
Promoter
Terminator
Transcription factors
Initiation, Elongation, & Termination
Termplate strand/non-template strand
RNA nucleotides
Transcription initiation complex
TATA box
5' cap
Poly-A tail
Introns
Exons
snRPs
Spliceosome

Translation

mRNA, rRNA, & tRNA
codons & anti-codons
Ribosome
A, P, & E sites
Amino acids (specify which types)
Amino acid attachment site
Animoacyl-tRNA synthetase
Hydrogen bonds
ATP & GTP
Small & large subunits
Polypeptide chain
Exit tunnel
Wobble
Translocation
Initiation, Elongation, & Termination

Claymation Movie Scoring Rubric:

Central Dogma Project Rubric
File Size: 12 kb
File Type: xlsx
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